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Article

p53 protein accumulation and gene mutation in the progression of human prostate carcinoma.

Journal of the National Cancer Institute - 20 Oct 1993

Navone N M, Troncoso P, Pisters L L, Goodrow T L, Palmer J L, Nichols W W, von Eschenbach A C, Conti C J

Abstract excerpt

BACKGROUND: Nuclear accumulation of p53 protein has been shown to be strongly associated with missense p53 mutations. Studies of nuclear accumulation of p53 protein in prostate carcinoma cells have to date been confined to material from primary tumors. PURPOSE: We studied the accumulation of p53 protein in specimens obtained from primary and metastatic sites of prostate carcinoma. By examining the accumulation of...

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PMID: 7692074
DOI: 10.1093/jnci/85.20.1657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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