Article
p53, retinoblastoma, and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract.
Archives of otolaryngology--head & neck surgery - 1 Oct 1993
Lee N K, Ye Y W, Chen J, Li X, Waber P G, Nisen P D
Abstract excerpt
OBJECTIVE: The primary objective of this study was to determine the incidence of p53 and retinoblastoma tumor suppressor gene mutations and human papillomavirus infection in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract. The secondary objective was to associa...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- DNA Probes, HPV
- DNA, Neoplasm
- Digestive System
- Genes, Retinoblastoma
- Genes, p53
- Head
- Head and Neck Neoplasms
- Heterozygote
- Humans
- Molecular Sequence Data
- Mucous Membrane
- Mutation
- Papillomaviridae
- Papillomavirus Infections
- Polymerase Chain Reaction
- Polymorphism, Genetic