Article
Comparative p53 mutational analysis of multiple primary cancers of the upper aerodigestive tract.
Surgery - 1 Jul 1996
Ribeiro U, Safatle-Ribeiro A V, Posner M C, Rosendale B, Bakker A, Swalsky P A, Kim R, Reynolds J C, Finkelstein S D
Abstract excerpt
BACKGROUND: Tumors arising in the upper aerodigestive tract (UAT) are often associated with predisposing factors that place the patient at risk for development of multiple synchronous or metachronous tumors. The aim of this study was to evaluate p53 as a susceptibility gene in UAT malignancy. METHODS: Seventeen patients with 41 separate primary tumors involving esophagus (n = 15), larynx (n = 14), pharynx (n =...
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