Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.

doi:10.1111/j.1600-0714.1996.tb00266.x

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Article

Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 1996

Sakata K

Abstract excerpt

The frequencies of mutations in the adenomatous polyposis coli (APC). p53, and p16 (MTS1; multiple tumor suppressor 1/CDK4I; cyclin-dependent kinase 4 inhibitor) tumor suppressor genes were investigated in 23 oral squamous cell carcinomas (SCCs). Loss of heterozygosity (LOH) at the retinoblastoma...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 9
DNA Mutational Analysis
DNA, Neoplasm
Female
Gene Deletion
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, p53
Genes, ras
Humans
Male
Microsatellite Repeats
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 8887073
DOI: 10.1111/j.1600-0714.1996.tb00266.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8887073-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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