Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 1996

Sakata K

Abstract excerpt

The frequencies of mutations in the adenomatous polyposis coli (APC). p53, and p16 (MTS1; multiple tumor suppressor 1/CDK4I; cyclin-dependent kinase 4 inhibitor) tumor suppressor genes were investigated in 23 oral squamous cell carcinomas (SCCs). Loss of heterozygosity (LOH) at the retinoblastoma (Rb) gene locus and on chromosomes 3p (VHL; von Hippel-Lindau disease tumor suppressor gene locus), 5q (APC) and 9p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to DNA, Neoplasm

Share to Gene Deletion

Share to Genes, p53

Share to Genes, ras

Share to Microsatellite Repeats

Source

Identifiers

PMID: 8887073
DOI: 10.1111/j.1600-0714.1996.tb00266.x

Genes

APC
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.PMID 8887073Read ↗

Alterations of p16/CDKN2, p53 and ras genes in oral squamous cell carcinomas and premalignant lesions.Semantic proximity Read ↗

Aberrations of tumor-suppressor genes (p53, apc, mcc and Rb) in esophageal squamous-cell carcinoma.Semantic proximity Read ↗

Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck.Semantic proximity Read ↗

Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations.Semantic proximity Read ↗

The p53 tumor-suppressor gene and ras oncogene mutations in oral squamous-cell carcinoma.Semantic proximity Read ↗

Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma.Semantic proximity Read ↗

Evaluation of p53 gene mutation and loss of heterozygosity of 3p, 9p and 17p in precancerous lesions of 29 lung cancer patients.Semantic proximity Read ↗

p53, retinoblastoma, and human papillomavirus in squamous cell carcinoma and adjacent normal mucosa of the upper aerodigestive tract.Semantic proximity Read ↗

p53 gene mutations in human skin cancers and precancerous lesions: comparison with immunohistochemical analysis.Semantic proximity Read ↗

Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinoma.Semantic proximity Read ↗

Characterization of p53 gene mutations in a Brazilian population with oral squamous cell carcinomas.Semantic proximity Read ↗

DNA aberrations at the retinoblastoma gene locus in human squamous cell carcinomas of the lung.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.