DNA aberrations at the retinoblastoma gene locus in human squamous cell carcinomas of the lung.

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Article

DNA aberrations at the retinoblastoma gene locus in human squamous cell carcinomas of the lung.

Oncogene - 1 Jan 1994

Sachse R, Murakami Y, Shiraishi M, Hayashi K, Sekiya T

Abstract excerpt

We detected DNA aberrations at the RB locus in surgical specimens of human primary non-small cell lung carcinoma by single-strand conformation polymorphism analysis of polymerase chain reaction products amplified from regions of exons 2 to 27 including parts of the flanking intron sequences. Dete...

Topics

Base Sequence
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Chromosome Deletion
Chromosome Mapping
DNA, Neoplasm
Genes, Retinoblastoma
Humans
Lung Neoplasms
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8302602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8302602-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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