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Article

Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines.

British journal of cancer - 1 Jun 1993

Burns J E, Baird M C, Clark L J, Burns P A, Edington K, Chapman C, Mitchell R, Robertson G, Soutar D, Parkinson E K

Abstract excerpt

Using immunocytochemical and Western blotting techniques we have demonstrated the presence of abnormally high levels of p53 protein in 8/24 (33%) of human squamous cell carcinomas (SCC) and 9/18 (50%) of SCC cell lines. There was a correlation between the immunocytochemical results obtained with eight SCC samples and their corresponding cell lines. Direct sequencing of PCR-amplified, reverse transcribed, p53 mRNA...

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Share to Base Sequence
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Genes, p53

Share to Immunohistochemistry

Share to Molecular Sequence Data

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 8390283
DOI: 10.1038/bjc.1993.238
PMCID: PMC1968513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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