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Article

Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.

Oncogene - 1 May 1992

Sakai E, Tsuchida N

Abstract excerpt

Oral squamous cell carcinoma cell lines and tumor tissues used for cell line establishment were examined for p53 tumor-suppressor gene mutation using cellular DNAs and RNAs. For sensitive and rapid detection, a newly designed two-stage filtration strategy was used. Full advantage was taken of the...

Topics

Amino Acid Sequence
Base Sequence
Carcinoma, Squamous Cell
Chromosome Mapping
Exons
Genes, p53
Humans
Molecular Sequence Data
Mouth Neoplasms
Mutation
Polymerase Chain Reaction
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 1570156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1570156-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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