Article
[Cosegregation studies in spontaneously hypertensive rats].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1993
Katsuya T, Ogihara T
Abstract excerpt
SHR (spontaneously hypertensive rat) is the most popular genetic hypertensive model rat. Using the F2 progeny obtained from SHR and normotensive rats, for example, WKY (Wistar-Kyoto rat), many cosegregation studies to find the genes responsible for blood pressure have been done. In this review, we present some studies using F2 rats concerning candidate genes, renin, kallikrein, sodium potassium-ATPase, heat shock...
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