Article
Analysis and comparison of new candidate loci for hypertension between genetic hypertensive rat strains.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Mar 1996
Takami S, Higaki J, Miki T, Katsuya T, Nakata Y, Rakugi H, Serikawa T, Ogihara T
Abstract excerpt
To search for the genes that determine the level of blood pressure, we performed linkage analyses using rat microsatellite markers in two sets of F2 rats derived from two hypertensive rat strains and one normotensive rat strain. In the first F2 progeny obtained from spontaneously hypertensive rats and Wistar-Kyoto rats, it was found that two different loci cosegregated with blood pressure. One was...
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