Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetics of the SA-gene: cosegregation with hypertension and mapping to rat chromosome 1.

Journal of hypertension - 1 Jan 1993

Lindpaintner K, Hilbert P, Ganten D, Nadal-Ginard B, Inagami T, Iwai N

Abstract excerpt

OBJECTIVES: The SA-gene shows markedly higher levels of expression in the kidneys of spontaneously hypertensive rats (SHR) than in their non-hypertensive reference strain, the Wistar-Kyoto (WKY) rat. Based on the important role of the kidney in blood pressure regulation, the possibility has been raised that this gene, the translational product of which remains unknown, may participate in the pathogenesis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Genetic Linkage
Share to Hypertension

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Restriction Fragment Length

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Source

Identifiers

PMID: 8094726
DOI: 10.1097/00004872-199301000-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetics of the SA-gene: cosegregation with hypertension and mapping to rat chromosome 1.PMID 8094726Read ↗

Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.Semantic proximity Read ↗

A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure.Semantic proximity Read ↗

Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.Semantic proximity Read ↗

Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure.Semantic proximity Read ↗

Identification of a candidate gene responsible for the high blood pressure of spontaneously hypertensive rats.Semantic proximity Read ↗

Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension.Semantic proximity Read ↗

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

Genetic analysis of the SA and Na+/K+-ATPase alpha1 genes in the Milan hypertensive rat.Semantic proximity Read ↗

Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity.Semantic proximity Read ↗

The rat SA gene shows genotype-dependent tissue-specific expression.Semantic proximity Read ↗

[Cosegregation studies in spontaneously hypertensive rats].Semantic proximity Read ↗

Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.