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Article

Cosegregation of spontaneously hypertensive rat renin gene with elevated blood pressure in an F2 generation.

Journal of hypertension - 1 Aug 1998

Yu H, Harrap S B, Di Nicolantonio R

Abstract excerpt

OBJECTIVE: To investigate the role of the renin gene in the hypertension of the spontaneously hypertensive rat (SHR) of the Okamoto strain. METHODS: We determined whether the SHR renin allele was cosegregated with high blood pressure in 137 F2 rats derived from inbred SHR and Wistar-Kyoto rats. Systolic blood pressure in conscious rats was measured by the tail-cuff method, whereas mean arterial pressure was...

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Identifiers

PMID: 9794718
DOI: 10.1097/00004872-199816080-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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