Cosegregation of spontaneously hypertensive rat renin gene with elevated blood pressure in an F2 generation.

doi:10.1097/00004872-199816080-00010

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Article

Cosegregation of spontaneously hypertensive rat renin gene with elevated blood pressure in an F2 generation.

Journal of hypertension - 1 Aug 1998

Yu H, Harrap S B, Di Nicolantonio R

Abstract excerpt

OBJECTIVE: To investigate the role of the renin gene in the hypertension of the spontaneously hypertensive rat (SHR) of the Okamoto strain. METHODS: We determined whether the SHR renin allele was cosegregated with high blood pressure in 137 F2 rats derived from inbred SHR and Wistar-Kyoto rats. S...

Topics

Animals
Base Sequence
Blood Pressure
Body Weight
Crosses, Genetic
DNA Primers
Female
Genotype
Hypertension
Male
Organ Size
Phenotype
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Renin
Systole

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