Cosegregation of the renin gene with an increase in mean arterial blood pressure in the F2 rats of SHR-WKY cross.

doi:10.3109/10641969309041642

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Article

Cosegregation of the renin gene with an increase in mean arterial blood pressure in the F2 rats of SHR-WKY cross.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Sept 1993

Sun L, McArdle S, Chun M, Wolff D W, Pettinger W A

Abstract excerpt

Using the restriction endonuclease, Bgl I, Samani et al. found a restriction fragment length polymorphism (RFLP) for the renin gene in spontaneously hypertensive rats (SHR) and its normotensive control Wistar-Kyoto (WKY) rats (1). This RFLP was confirmed in our laboratory in SHR and WKY rats usin...

Topics

Alleles
Animals
Blood Pressure
Crosses, Genetic
DNA
Female
Genotype
Hypertension
Male
Polymorphism, Restriction Fragment Length
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Renin

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