Article
Sites and types of p53 mutations in an unselected series of colorectal cancers in The Netherlands.
Anticancer research - 1 Jan 2000
Van Den Broek M H, Renault B, Fodde R, Verspaget H, Griffioen G, Khan P M
Abstract excerpt
An unselected series of colorectal adenocarcinomas together with their corresponding normal mucosa, derived from 24 Dutch patients, was investigated for the loss of a marker mapping close to the region of p53 on chromosome 17p and for mutations in exons 5, 6, 7 and 8 of the p53 gene. The observed...
Topics
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Base Sequence
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Codon
- Colorectal Neoplasms
- Exons
- Female
- Genes, p53
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Netherlands
