Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of a single-copy tRNA affects microtubule function in Saccharomyces cerevisiae.

Genetics - 1 Dec 1993

Reijo R A, Cho D S, Huffaker T C

Abstract excerpt

rts1-1 was identified as an extragenic suppressor of tub2-104, a cold-sensitive allele of the sole gene encoding beta-tubulin in the yeast, Saccharomyces cerevisiae. In addition, rts1-1 cells are heat sensitive and resistant to the microtubule-destabilizing drug, benomyl. The rts1-1 mutation is a deletion of approximately 5 kb of genomic DNA on chromosome X that includes one open reading frame and three tRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Phenotype

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8307335
DOI: 10.1093/genetics/135.4.955
PMCID: PMC1205756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of a single-copy tRNA affects microtubule function in Saccharomyces cerevisiae.PMID 8307335Read ↗

Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules.Semantic proximity Read ↗

High copies of SUM1 enhance the stability of wild-type microtubules against adverse conditions in Saccharomyces cerevisiae.Semantic proximity Read ↗

The essential yeast Tcp1 protein affects actin and microtubules.Semantic proximity Read ↗

Systematic mutational analysis of the yeast beta-tubulin gene.Semantic proximity Read ↗

Suppression of a conditional mutation in alpha-tubulin by overexpression of two checkpoint genes.Semantic proximity Read ↗

Characterisation of fission yeast alp11 mutants defines three functional domains within tubulin-folding cofactor B.Semantic proximity Read ↗

Structure-function relationships in yeast tubulins.Semantic proximity Read ↗

A high dose of the STM1 gene suppresses the temperature sensitivity of the tom1 and htr1 mutants in Saccharomyces cerevisiae.Semantic proximity Read ↗

The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein.Semantic proximity Read ↗

Multicopy STS1 restores both protein transport and ribosomal RNA stability in a new yeast sec23 mutant allele.Semantic proximity Read ↗

An alpha-tubulin mutant demonstrates distinguishable functions among the spindle assembly checkpoint genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Nucleotide sequence of the SAC2 gene of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.