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Article

The essential yeast Tcp1 protein affects actin and microtubules.

Molecular biology of the cell - 1 Oct 1994

Ursic D, Sedbrook J C, Himmel K L, Culbertson M R

Abstract excerpt

Previously, we showed that the yeast Saccharomyces cerevisiae cold-sensitive mutation tcp1-1 confers growth arrest concomitant with cytoskeletal disorganization and disruption of microtubule-mediated processes. We have identified two new recessive mutations, tcp1-2 and tcp1-3, that confer heat- and cold-sensitive growth. Cells carrying tcp1 alleles were analyzed after exposure to the appropriate restrictive...

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Identifiers

PMID: 7865875
DOI: 10.1091/mbc.5.10.1065
PMCID: PMC301131

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