Multicopy STS1 restores both protein transport and ribosomal RNA stability in a new yeast sec23 mutant allele.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Multicopy STS1 restores both protein transport and ribosomal RNA stability in a new yeast sec23 mutant allele.

European journal of cell biology - 1 Dec 1993

Liang S, Lacroute F, Képès F

Abstract excerpt

A thermosensitive mutant was selected on the basis of its resistance after a heat shock to the lethal effects of lomofungin, a drug that inhibits RNA synthesis. We demonstrate that the single mutation conferring thermosensitivity and lomofungin resistance is heteroallelic to sec23-1. This new all...

Topics

ATP-Binding Cassette Transporters
Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Transport
Endoplasmic Reticulum
Fungal Proteins
Genes, Fungal
Genes, Suppressor
Golgi Apparatus
Molecular Sequence Data
Mutation
RNA, Fungal
RNA, Ribosomal
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Source

Open in PubMed

Identifiers

PMID: 7925484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7925484-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics