Article
Multicopy STS1 restores both protein transport and ribosomal RNA stability in a new yeast sec23 mutant allele.
European journal of cell biology - 1 Dec 1993
Liang S, Lacroute F, Képès F
Abstract excerpt
A thermosensitive mutant was selected on the basis of its resistance after a heat shock to the lethal effects of lomofungin, a drug that inhibits RNA synthesis. We demonstrate that the single mutation conferring thermosensitivity and lomofungin resistance is heteroallelic to sec23-1. This new allele of sec23 is designated sec23-11. The yeast SEC23 gene has previously been reported to function in protein transport...
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