Article
The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein.
Proceedings of the National Academy of Sciences of the United States of America - 26 Oct 1999
Morehouse H, Buratowski R M, Silver P A, Buratowski S
Abstract excerpt
Two high copy suppressors of temperature-sensitive TATA-binding protein (TBP) mutants were isolated. One suppressor was TIF51A, which encodes eukaryotic translation initiation factor 5A. The other high copy suppressor, YGL241W, also known as KAP114, is one of 14 importin/karyopherin proteins in yeast. These proteins mediate the transport of specific macromolecules into and out of the nucleus. Cells lacking Kap114...
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