Article
Functional interactions within adenovirus E1A protein complexes.
Oncogene - 1 Feb 1994
Barbeau D, Charbonneau R, Whalen S G, Bayley S T, Branton P E
Abstract excerpt
The transforming potential of adenovirus E1A oncogene products derives largely from the formation of complexes with cellular proteins, including the p105Rb tumor suppressor and a related p107 species, p130 and p300 proteins, and cyclin A (p60cycA). Extensive quantitative analyses using E1A deleti...
Topics
- Adenovirus E1A Proteins
- Amino Acid Sequence
- Blotting, Western
- Cell Cycle
- Chromatography, Thin Layer
- Cyclins
- Electrophoresis, Polyacrylamide Gel
- Humans
- KB Cells
- Molecular Sequence Data
- Mutation
- Peptide Mapping
