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Article

Functional interactions within adenovirus E1A protein complexes.

Oncogene - 1 Feb 1994

Barbeau D, Charbonneau R, Whalen S G, Bayley S T, Branton P E

Abstract excerpt

The transforming potential of adenovirus E1A oncogene products derives largely from the formation of complexes with cellular proteins, including the p105Rb tumor suppressor and a related p107 species, p130 and p300 proteins, and cyclin A (p60cycA). Extensive quantitative analyses using E1A deletion mutants identified unique binding patterns for each of these polypeptides within the amino terminus and conserved...

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PMID: 8290250

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