Article
Interaction between the HPV E7 oncoprotein and the transcriptional coactivator p300.
Oncogene - 11 Sept 2003
Bernat Agnieszka, Avvakumov Nikita, Mymryk Joe S, Banks Lawrence
Abstract excerpt
Infection with high-risk human papillomaviruses (HPV) can lead to the development of cervical cancer. This process depends on the interaction of the virus-encoded oncoproteins, E6 and E7, with a variety of host regulatory proteins. As E7 shares both functional and structural similarities with the Adenovirus E1a (Ad E1a) protein, we were interested in investigating the possible interactions between E7 and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
