Article
Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia.
Pharmacogenetics - 1 Oct 1993
Ilett K F, Chiswell G M, Spargo R M, Platt E, Minchin R F
Abstract excerpt
N-Acetyltransferases (NAT1, NAT2) play an important role in biotransformation of a number of drugs and carcinogens. A polymorphism in the metabolism of such compounds by NAT2 has been known for many years but it is only recently that the underlying molecular genetics has been elucidated. In the present study, we have correlated acetylation phenotype and genotype in a group of 49 Australian Aborigines (26 males...
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