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Article

Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia.

Pharmacogenetics - 1 Oct 1993

Ilett K F, Chiswell G M, Spargo R M, Platt E, Minchin R F

Abstract excerpt

N-Acetyltransferases (NAT1, NAT2) play an important role in biotransformation of a number of drugs and carcinogens. A polymorphism in the metabolism of such compounds by NAT2 has been known for many years but it is only recently that the underlying molecular genetics has been elucidated. In the p...

Topics

Acetylation
Adolescent
Adult
Aged
Aged, 80 and over
Arylamine N-Acetyltransferase
Australia
Dapsone
Female
Genotype
Humans
Leprosy
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Polymorphism, Genetic

Australian Aboriginal and Torres Strait Islander Peoples

Source

Identifiers

PMID: 8287065
DOI: 10.1097/00008571-199310000-00006

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8287065-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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