Article
N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans.
Biochemical pharmacology - 8 Aug 1991
Hickman D, Sim E
Abstract excerpt
N-Acetyltransferase (NAT) isoenzymes are encoded at two loci. One locus encodes an NAT which is expressed widely in tissues, does not vary amongst human individuals and is termed monomorphic NAT (mNAT). The second locus encodes an NAT which is termed polymorphic NAT (pNAT), has a distinct tissue distribution and is responsible for the difference in ability between individuals in acetylating certain arylamine...
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