Article
Discordance between N-acetyltransferase 2 phenotype and genotype in a population of Hmong subjects.
Journal of clinical pharmacology - 1 Jul 2006
Straka Robert J, Burkhardt R Todd, Lang Nicholas P, Hadsall Kelly Z, Tsai Michael Y
Abstract excerpt
Polymorphisms of N-acetyltransferase 2 (NAT2) acetylation may influence drug toxicities and efficacy and are associated with a differential susceptibility to select cancers. Acetylation phenotype may have clinical implications. The purposes of this study were to determine the genetic basis of an apparent predominance of slow acetylation phenotype and to assess concordance with genotype in a population of Hmong...
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