Article
Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity.
American journal of human genetics - 1 Sept 1995
Cascorbi I, Drakoulis N, Brockmöller J, Maurer A, Sperling K, Roots I
Abstract excerpt
The polymorphic arylamine N-acetyltransferase (NAT2; EC 2.3.1.5) is supposed to be a susceptibility factor for several drug side effects and certain malignancies. A group of 844 unrelated German subjects was genotyped for their acetylation type, and 563 of them were also phenotyped. Seven mutatio...
Topics
- Alleles
- Arylamine N-Acetyltransferase
- Base Sequence
- Genetic Linkage
- Genotype
- Humans
- Molecular Sequence Data
- Mutation
- Phenotype
- Polymerase Chain Reaction
- White People