Article
[Clinical relevance of N-acetyltransferase type 2 (NAT2) genetic polymorphism].
Therapie - 1 Jan 2000
Furet Y, Bechtel Y, Le Guellec C, Bechtel P R, Autret-Leca E, Paintaud G
Abstract excerpt
Polymorphic N-acetyltransferase (NAT2) is involved in the metabolism of several compounds relevant in pharmacology or toxicology, with diverse clinical consequences. Inter-ethnic variations in distribution of the acetylation phenotype are significant. The caffeine test is most often used to assess the acetylation phenotype and to identify rapid and slow acetylators. The NAT2 phenotype could account for the...
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