Article
N-acetyltransferase polymorphism among northern Sudanese.
Human biology - 1 Aug 2007
Al-Yahyaee Said, Gaffar Uzma, Al-Ameri Maryam M, Qureshi Mansoor, Zadjali Fahad, Ali Baderldin H, Bayoumi Riad
Abstract excerpt
Interindividual and interethnic differences in allele frequencies of N-acetyltransferase (NAT2) single nucleotide polymorphisms (SNPs) are responsible for phenotypic variability of adverse drug reactions and susceptibility to cancer. We genotyped the seven NAT2 common SNPs in 127 randomly selected unrelated northern Sudanese subjects using allele-specific and RFLP polymerase chain reaction (PCR) based methods....
Topics
- Adolescent
- Adult
- Alleles
- Arylamine N-Acetyltransferase
- Child
- Computers, Molecular
- Female
- Genotype
- Geography
- Haplotypes
- Humans
- Male