Correlation between acetylation phenotype and genotype in Chinese women.

doi:10.1007/s002280000203

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Article

Correlation between acetylation phenotype and genotype in Chinese women.

European journal of clinical pharmacology - 1 Dec 2000

Zhao B, Seow A, Lee E J, Lee H P

Abstract excerpt

OBJECTIVE: The acetylation polymorphism is a common inherited variation in human drug and carcinogen metabolism. Because N-acetyltransferase (NAT2) is important for the detoxification and/or bioactivation of drugs and carcinogens, this polymorphism has important implications in therapeutics and cancer susceptibility. A high correlation between acetylation phenotype and genotype has been demonstrated in several...

Topics

Acetylation
Adult
Aged
Aged, 80 and over
Arylamine N-Acetyltransferase
Caffeine
China
Female
Genotype
Humans
Middle Aged
Phenotype
Phosphoric Diester Hydrolases
Polymorphism, Genetic
Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 11214777
DOI: 10.1007/s002280000203

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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