Article
Correlation between acetylation phenotype and genotype in Chinese women.
European journal of clinical pharmacology - 1 Dec 2000
Zhao B, Seow A, Lee E J, Lee H P
Abstract excerpt
OBJECTIVE: The acetylation polymorphism is a common inherited variation in human drug and carcinogen metabolism. Because N-acetyltransferase (NAT2) is important for the detoxification and/or bioactivation of drugs and carcinogens, this polymorphism has important implications in therapeutics and cancer susceptibility. A high correlation between acetylation phenotype and genotype has been demonstrated in several...
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