Article
Arylamine N-acetyltransferase 2 polymorphism in the ethnic populations of South India.
International journal of molecular medicine - 1 Jan 2003
Anitha A, Banerjee Moinak
Abstract excerpt
The human N-acetylation polymorphism is a genetic trait phenotypically reflected by differences in N-acetyltransferase (NAT) activity with therapeutic agents (rapid and slow acetylation). Acetylation polymorphism arises from the allelic variations in human arylamine N-acetyltransferase 2 gene (NAT2), which results in the production of NAT2 proteins with variable enzyme activity or stability. Certain NAT2 traits...
Topics
- Arylamine N-Acetyltransferase
- Base Sequence
- DNA Primers
- Enzyme Stability
- Ethnicity
- Genetic Variation
- Genotype
- Humans
- India
- Kinetics
- Mutation
- Polymorphism, Genetic
