Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.

doi:10.1097/00008571-199604000-00004

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Article

Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.

Pharmacogenetics - 1 Apr 1996

Deloménie C, Sica L, Grant D M, Krishnamoorthy R, Dupret J M

Abstract excerpt

The hepatic N-acetyltransferase enzyme encoded by the NAT2* gene locus is responsible for the human polymorphic acetylation of numerous arylamine or hydrazine-containing drugs and xenobiotics including AIDS-related therapeutic agents such as isoniazid and sulphonamides. The genetic basis underlyi...

Topics

Acetylation
Alleles
Arylamine N-Acetyltransferase
Base Sequence
Black People
DNA Primers
Gabon
Gene Frequency
Genotype
Humans
Liver
Mali
Polymorphism, Genetic
White People
Black or African American

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