Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.

Pharmacogenetics - 1 Apr 1996

Deloménie C, Sica L, Grant D M, Krishnamoorthy R, Dupret J M

Abstract excerpt

The hepatic N-acetyltransferase enzyme encoded by the NAT2* gene locus is responsible for the human polymorphic acetylation of numerous arylamine or hydrazine-containing drugs and xenobiotics including AIDS-related therapeutic agents such as isoniazid and sulphonamides. The genetic basis underlying the human acetylation polymorphism has been extensively studied in several populations but native African...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genotype

Share to Polymorphism, Genetic

Share to White People

Source

Identifiers

PMID: 9156695
DOI: 10.1097/00008571-199604000-00004

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.PMID 9156695Read ↗

Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene.Semantic proximity Read ↗

Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity.Semantic proximity Read ↗

Polymorphism of human acetyltransferases.Semantic proximity Read ↗

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid.Semantic proximity Read ↗

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.Semantic proximity Read ↗

Study of NAT2 genetic polymorphism in West African subjects: example of an healthy non-smoker Senegalese population.Semantic proximity Read ↗

Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey.Semantic proximity Read ↗

Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1.Semantic proximity Read ↗

Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene.Semantic proximity Read ↗

NAT2 gene diversity and its evolutionary trajectory in the Americas.Semantic proximity Read ↗

Polymorphisms of N-acetyltransferase genes.Semantic proximity Read ↗

Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.