Activation of the prespore and spore cell pathway of Dictyostelium differentiation by cAMP-dependent protein kinase and evidence for its upstream regulation by ammonia.

doi:10.1002/j.1460-2075.1993.tb05900.x

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Article

Activation of the prespore and spore cell pathway of Dictyostelium differentiation by cAMP-dependent protein kinase and evidence for its upstream regulation by ammonia.

The EMBO journal - 1 Jun 1993

Hopper N A, Harwood A J, Bouzid S, Véron M, Williams J G

Abstract excerpt

Expression of a dominant inhibitor of the Dictyostelium cAMP-dependent protein kinase in prespore cells blocks their differentiation into spore cells. The resultant structures comprise a normal stalk supporting a bolus of cells that fail to express a sporulation-specific gene and that show greatl...

Topics

Ammonia
Animals
Dictyostelium
Gene Expression
Genes, Protozoan
Mutation
Protein Kinases
Protozoan Proteins
Spores

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