Article
Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity.
Development (Cambridge, England) - 1 Nov 1991
Haberstroh L, Galindo J, Firtel R A
Abstract excerpt
Previously, 5' deletion analysis revealed three important upstream regions within the regulatory region of the cAMP-induced, prespore gene SP60 of D. discoidium, each of which contains a CA-rich sequence element (CAE: consensus CACACAYYYCACACAAA/T). In this study, we have made site-directed mutations within these CAEs and examined their effect on reporter gene activity (luciferase or lacZ). Point mutations within...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
