Article
cAMP production by adenylyl cyclase G induces prespore differentiation in Dictyostelium slugs.
Development (Cambridge, England) - 1 Mar 2007
Alvarez-Curto Elisa, Saran Shweta, Meima Marcel, Zobel Jenny, Scott Claire, Schaap Pauline
Abstract excerpt
Encystation and sporulation are crucial developmental transitions for solitary and social amoebae, respectively. Whereas little is known of encystation, sporulation requires both extra- and intracellular cAMP. After aggregation of social amoebae, extracellular cAMP binding to surface receptors and intracellular cAMP binding to cAMP-dependent protein kinase (PKA) act together to induce prespore differentiation....
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