Article
Heterogeneity of subcellular localization of p53 protein in human glioblastomas.
Cancer research - 1 Jan 1994
Ali I U, Schweitzer J B, Ikejiri B, Saxena A, Robertson J T, Oldfield E H
Abstract excerpt
Immunohistochemical analysis of the p53 protein in human glioblastomas with known genetic profiles of p53 mutations and allele losses on chromosome 17p demonstrated a heterogeneous pattern of subcellular compartmentalization of the p53 protein. Tumors with a single wild type copy of the p53 gene...
Topics
- Base Sequence
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Cytoplasm
- Glioblastoma
- Humans
- Molecular Sequence Data
- Mutation
- Tumor Suppressor Protein p53
