Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneity of subcellular localization of p53 protein in human glioblastomas.

Cancer research - 1 Jan 1994

Ali I U, Schweitzer J B, Ikejiri B, Saxena A, Robertson J T, Oldfield E H

Abstract excerpt

Immunohistochemical analysis of the p53 protein in human glioblastomas with known genetic profiles of p53 mutations and allele losses on chromosome 17p demonstrated a heterogeneous pattern of subcellular compartmentalization of the p53 protein. Tumors with a single wild type copy of the p53 gene but with allelic deletions on chromosome 17p exhibit nuclear and/or cytoplasmic accumulation of p53, whereas tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytoplasm

Share to Glioblastoma

Share to Molecular Sequence Data

Share to Mutation

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8261427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Heterogeneity of subcellular localization of p53 protein in human glioblastomas.PMID 8261427Read ↗

Cytoplasmic localization of wild-type p53 in glioblastomas correlates with expression of vimentin and glial fibrillary acidic protein.Semantic proximity Read ↗

p53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing.Semantic proximity Read ↗

Role and mutational heterogeneity of the p53 gene in hepatocellular carcinoma.Semantic proximity Read ↗

A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme.Semantic proximity Read ↗

Differential subcellular p53 localization and function in N- and S-type neuroblastoma cell lines.Semantic proximity Read ↗

Comparative assessment of the functional p53 status in glioma cells.Semantic proximity Read ↗

Accumulation of wild-type p53 in meningiomas.Semantic proximity Read ↗

Accumulation of wild type p53 protein in human astrocytomas.Semantic proximity Read ↗

Expression of p53 and 17p allelic loss in colorectal carcinoma.Semantic proximity Read ↗

p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma.Semantic proximity Read ↗

Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.