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Article

Frequency of ultraviolet radiation-induced mutation at the hprt locus in repair-proficient murine fibroblasts transfected with the denV gene of bacteriophage T4.

Photochemistry and photobiology - 1 Sept 1993

Kusewitt D F, Budge C L, Anderson M M, Ryan S L, Ley R D

Abstract excerpt

The frequency of spontaneous and ultraviolet radiation (UVR)-induced mutation at the hprt locus was determined in control and denV-transfected, repair-proficient murine fibroblasts. Control cells removed an average of 25% of pyrimidine dimers induced by exposure to 150 J/m2 UVR from an FS40 sunla...

Topics

Animals
Bacteriophage T4
Cell Line
Cell Survival
DNA Repair
Deoxyribonuclease (Pyrimidine Dimer)
Endodeoxyribonucleases
Fibroblasts
Hypoxanthine Phosphoribosyltransferase
Mice
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pyrimidine Dimers

Transfection

Ultraviolet Rays

Source

Identifiers

PMID: 8234481
DOI: 10.1111/j.1751-1097.1993.tb09589.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8234481-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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