Article
Molecular characterization of hprt mutants induced by low- and high-LET radiations in human cells.
Mutation research - 1 Jan 1990
Whaley J M, Little J B
Abstract excerpt
Southern blotting techniques were employed to examine the spectrum of molecular alterations in DNA induced by internally emitting iodine isotopes and X-rays at and around the hprt locus in a human lymphoblastoid cell line. We analyzed 165 mutant clones using a cDNA probe for the human hprt locus, and 3 anonymous sequence probes for regions of the X chromosome which are linked to hprt. The results were compared...
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