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Article

Altered UV resistance and UV mutational spectrum in repair-proficient murine fibroblasts expressing endonuclease V.

Mutation research - 1 Mar 1998

Kusewitt D F, Dyble J, Sherburn T E, Ryan S L, Ji J Y

Abstract excerpt

In previously reported studies, we transfected repair-proficient murine fibroblasts with the denV gene of bacteriophage T4 and showed that expression of encoded endonuclease V markedly enhanced cyclobutane pyrimidine dimer (CPD) repair and reduced the frequency of ultraviolet radiation (UV)-induced mutations. In the present studies, we compared the spectra of UV-induced mutations at the hprt locus in...

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Source

Identifiers

PMID: 9637244
DOI: 10.1016/s0921-8777(98)00004-4

Genes

CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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