Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells.

doi:10.1016/0027-5107(91)90224-c

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Article

Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells.

Mutation research - 1 Nov 1991

Menichini P, Vrieling H, van Zeeland A A

Abstract excerpt

The mutation spectrum induced by UV light has been determined at the hprt locus for both cultured normal (AA8) and UV-sensitive (UV-5) Chinese hamster ovary cells to investigate the effect of DNA repair on the nature of induced mutations. DNA base-pair changes of 23 hprt mutants of AA8 and of 28...

Topics

Animals
Base Sequence
CHO Cells
Cell Line
Cell Survival
Cricetinae
DNA
DNA Mutational Analysis
DNA Repair
Hypoxanthine Phosphoribosyltransferase
Molecular Sequence Data
Mutation
Polydeoxyribonucleotides
Polymerase Chain Reaction
Ultraviolet Rays

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