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Article

Pursuing the voltage sensor of a voltage-gated mammalian potassium channel.

The Journal of biological chemistry - 15 Nov 1993

Tytgat J, Nakazawa K, Gross A, Hess P

Abstract excerpt

Ion channels are generally classified as voltage- or ligand-gated channels based upon their ability to respond to a change in the transmembrane voltage or to a specific ligand interaction. The voltage sensor of voltage-gated ion channels is thought to be contained within the fourth putative transmembrane segment, S4, and is characterized by basic residues typically spaced apart. Thus far, a full understanding of...

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PMID: 8226910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Research trail→

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Pursuing the voltage sensor of a voltage-gated mammalian potassium channel.PMID 8226910Read ↗

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Gating consequences of charge neutralization of arginine residues in the S4 segment of K(v)7.2, an epilepsy-linked K+ channel subunit.Semantic proximity Read ↗

Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP.Semantic proximity Read ↗

Coupling between residues on S4 and S1 defines the voltage-sensor resting conformation in NaChBac.Semantic proximity Read ↗

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