Loss of heterozygosity for 10q22-10qter in malignant melanoma progression.

Article

Loss of heterozygosity for 10q22-10qter in malignant melanoma progression.

Cancer research - 15 Jun 1994

Herbst R A, Weiss J, Ehnis A, Cavenee W K, Arden K C

Abstract excerpt

Karyotypic and molecular data indicate that genetic events involving the chromosome region 10q22-10qter may be related to tumorigenesis in malignant melanoma. To test this we analyzed 10 polymorphic microsatellite repeats in the region 10q22-qter, using a polymerase chain reaction-based assay for...

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 10
DNA, Neoplasm
Heterozygote
Humans
Melanoma

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