Allele loss on chromosome 11q and microsatellite instability in malignant melanoma.

doi:10.1016/0959-8049(96)00198-0

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Article

Allele loss on chromosome 11q and microsatellite instability in malignant melanoma.

European journal of cancer (Oxford, England : 1990) - 1 Sept 1996

Tomlinson I P, Beck N E, Bodmer W F

Abstract excerpt

Loss of heterozygosity (allele loss, LOH) occurs frequently on the long arm of chromosome 11 in several types of cancer. We analysed 32 melanomas (almost all metastatic lesions) for allele loss at eight loci along the length of chromosome 11 (ptel-D11S922-D11S899-D11S1324-D11S1313-++ +D11S901-NCA...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Chromosome Deletion
Chromosomes, Human, Pair 11
DNA Replication
DNA, Neoplasm
Humans
Melanoma
Microsatellite Repeats
Middle Aged
Polymorphism, Single-Stranded Conformational

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