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Article

Allele loss on chromosome 11q and microsatellite instability in malignant melanoma.

European journal of cancer (Oxford, England : 1990) - 1 Sept 1996

Tomlinson I P, Beck N E, Bodmer W F

Abstract excerpt

Loss of heterozygosity (allele loss, LOH) occurs frequently on the long arm of chromosome 11 in several types of cancer. We analysed 32 melanomas (almost all metastatic lesions) for allele loss at eight loci along the length of chromosome 11 (ptel-D11S922-D11S899-D11S1324-D11S1313-++ +D11S901-NCAM-D11S29-D11S968-qtel). The highest frequency of loss (38%) was at D11S29 (11q23.3). Of 13 melanomas which had lost an...

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Identifiers

PMID: 8983292
DOI: 10.1016/0959-8049(96)00198-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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