Allelotypes of primary cutaneous melanoma and benign melanocytic nevi.

Article

Allelotypes of primary cutaneous melanoma and benign melanocytic nevi.

Cancer research - 1 Feb 1996

Healy E, Belgaid C E, Takata M, Vahlquist A, Rehman I, Rigby H, Rees J L

Abstract excerpt

A multistep genetic model of tumorigenesis, based on genetic alterations in benign and primary malignant lesions, has been proposed for neoplasms such as colonic carcinoma. However, evidence for a similar genetic progression in melanoma has relied heavily on findings in cultured lesions or metast...

Topics

Alleles
Chromosomes, Human, Pair 9
DNA, Neoplasm
Gene Deletion
Heterozygote
Humans
Melanoma
Nevus, Pigmented
Skin Neoplasms

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