Article
A genetic model of melanoma tumorigenesis based on allelic losses.
Genes, chromosomes & cancer - 1 Feb 1995
Walker G J, Palmer J M, Walters M K, Hayward N K
Abstract excerpt
Previous karyotypic studies have indicated a possible series of non-random chromosomal events involved in progression of melanoma. We sought to verify and augment this model of melanocyte tumorigenesis by studying allelic deletions of markers mapping to these regions in 30 matched pairs of melano...
Topics
- Alleles
- Chromosome Deletion
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 6
- Chromosomes, Human, Pair 7
- Chromosomes, Human, Pair 9
- DNA, Neoplasm
- Genotype
- Humans
- Melanoma
- Models, Genetic