Article
Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers.
Cancer research - 1 May 1995
Peiffer S L, Herzog T J, Tribune D J, Mutch D G, Gersell D J, Goodfellow P J
Abstract excerpt
Thirty-seven endometrial cancers were subjected to an allelotype analysis in an attempt to identify chromosomal regions that are lost in a significant portion of tumors and to identify tumors characterized by replication errors. Thirty-nine highly polymorphic microsatellite markers representing all chromosomal arms, excluding the X and the short arms of the acrocentrics, were examined. An average of 20...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- DNA
- DNA Replication
- DNA, Neoplasm
- DNA, Satellite
- Endometrial Neoplasms
- Female
- Gene Deletion
- Genes, Tumor Suppressor
