Article
Microsatellite instability and loss of heterozygosity in melanoma.
The Journal of investigative dermatology - 1 Oct 1995
Peris K, Keller G, Chimenti S, Amantea A, Kerl H, Höfler H
Abstract excerpt
Alterations in the repeat length of microsatellites have been identified recently in tumors arising in patients with hereditary nonpolyposis colon cancer and in several human sporadic tumors. We examined 40 sporadic melanomas and their corresponding nontumorous skin for microsatellite instability...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Chromosomes, Human
- DNA Repair
- DNA Replication
- DNA, Neoplasm
- Female
- Gene Deletion
- Genes, Tumor Suppressor
- Humans
