Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosomal allele loss in primary cutaneous melanoma is heterogeneous and correlates with proliferation.

The Journal of investigative dermatology - 1 Mar 1998

Böni R, Matt D, Voetmeyer A, Burg G, Zhuang Z

Abstract excerpt

Loss of heterozygosity at specific loci in neoplastic cells suggests the presence of a tumor suppressor gene within the deleted region. Using the microdissection technique, loss of heterozygosity has been identified in paraffin-embedded primary melanomas on chromosomes 1p and 9q. Our purpose was to determine loss of heterozygosity in primary cutaneous melanomas and to relate chromosomal alterations with cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Division
Share to Chromosomes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Chromosomes, Human, Pair 9

Share to Melanoma

Share to Polymorphism, Genetic

Share to Skin Neoplasms

Source

Identifiers

PMID: 9506438
DOI: 10.1046/j.1523-1747.1998.00109.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosomal allele loss in primary cutaneous melanoma is heterogeneous and correlates with proliferation.PMID 9506438Read ↗

Loss of heterozygosity in the MXI1 gene is a frequent occurrence in melanoma.Semantic proximity Read ↗

Genotypic analysis of primary and metastatic cutaneous melanoma.Semantic proximity Read ↗

Allelotypes of primary cutaneous melanoma and benign melanocytic nevi.Semantic proximity Read ↗

Heterogeneity of allelic deletions within melanoma metastases.Semantic proximity Read ↗

Allele losses in malignant melanoma reflect random events.Semantic proximity Read ↗

Loss of heterozygosity analysis of cutaneous melanoma and benign melanocytic nevi: laser capture microdissection demonstrates clonal genetic changes in acquired nevocellular nevi.Semantic proximity Read ↗

Loss of heterozygosity for 10q22-10qter in malignant melanoma progression.Semantic proximity Read ↗

Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas.Semantic proximity Read ↗

Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas.Semantic proximity Read ↗

Allele loss on chromosome 11q and microsatellite instability in malignant melanoma.Semantic proximity Read ↗

Identification of two distinct deletion targets at 11q23 in cutaneous malignant melanoma.Semantic proximity Read ↗

Analysis of tumor cell evolution in a melanoma: evidence of mutational and selective pressure for loss of p16ink4 and for microsatellite instability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.