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Article

Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer+ and Mer- diploid human fibroblasts.

Carcinogenesis - 1 May 1994

Yang J L, Lee P C, Lin S R, Lin J G

Abstract excerpt

N-Ethyl-N-nitrosourea (ENU) forms several major adducts upon reaction with DNA, of which ethylation at the O6 position of guanine and the O4, O2 and N3 positions of thymine have been implicated to be mutagenic lesions. To investigate what specific kinds of ENU-induced mutations were affected by the repair ability of O6-alkylguanine-DNA alkyltransferase (AGT), we examined the mutations in the hypoxanthine...

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Source

Identifiers

PMID: 8200099
DOI: 10.1093/carcin/15.5.939

Genes

AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer+ and Mer- diploid human fibroblasts.PMID 8200099Read ↗

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