Effect of ogt expression on mutation induction by methyl-, ethyl- and propylmethanesulphonate in Escherichia coli K12 strains.

doi:10.1007/BF00283431

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Article

Effect of ogt expression on mutation induction by methyl-, ethyl- and propylmethanesulphonate in Escherichia coli K12 strains.

Molecular & general genetics : MGG - 1 Mar 1994

Abril N, Hera C, Alejandre E, Rafferty J A, Margison G P, Pueyo C

Abstract excerpt

We have previously reported the isolation of an Escherichia coli K12 mutant that is extremely sensitive to mutagenesis by low doses of ethylating agents. We now show by Southern analysis that the mutation involves a gross deletion covering at least the ogt and fnr genes and that no O6-alkylguanin...

Topics

Alkylating Agents
Escherichia coli
Ethyl Methanesulfonate
Gene Expression
Genes, Bacterial
Mesylates
Methyl Methanesulfonate
Mutagenesis
Mutation
Sequence Deletion

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