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Article

The influence of DNA repair by Ogt alkyltransferase on the distribution of alkylnitrosourea-induced mutations in Escherichia coli.

Environmental and molecular mutagenesis - 1 Jan 1997

Vidal A, Abril N, Pueyo C

Abstract excerpt

To determine the influence of DNA repair by Ogt alkyltransferase on the distribution of alkylnitrosourea-induced mutations, we have analysed in Ogt-proficient and Ogt-deficient bacterial strains the DNA sequence changes of a total of 357 independent mutations occurring within the initial part of the lacl gene of Escherichia coli. The majority (>80%) of mutations induced by either N-ethyl-N nitrosourea (ENU) or...

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Identifiers

PMID: 9118970
DOI: 10.1002/(sici)1098-2280(1997)29:2<180::aid-em9>3.0.co;2-i

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