Article
Roles of two types of O6-methylguanine-DNA methyltransferases in DNA repair.
Mutation research - 1 Jan 1991
Takano K, Nakamura T, Sekiguchi M
Abstract excerpt
Escherichia coli possesses 2 types of O6-methylguanine-DNA methyltransferases, one inducible and the other constitutive. These enzymes are coded by the ada and the ogt genes, respectively. Using a synthetic ogt-specific probe, we mapped ogt at 29.4 min, near the 5'-flanking region of the nirR gen...
Topics
- Base Sequence
- Blotting, Southern
- Chromosome Mapping
- Chromosomes, Bacterial
- Cloning, Molecular
- DNA Repair
- Escherichia coli
- Genes, Bacterial
- Methylnitronitrosoguanidine
- Methyltransferases
- Molecular Sequence Data
- Mutation
- O(6)-Methylguanine-DNA Methyltransferase
- Oligonucleotide Probes
- Plasmids
- Restriction Mapping
