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Article

Reduction of GC --> TA transversion mutation by overexpression of MutS in Escherichia coli K-12.

Journal of bacteriology - 1 Sept 2000

Zhao J, Winkler M E

Abstract excerpt

Overexpression of the MutS repair protein significantly decreased the rate of lacZ GC --> TA transversion mutation in stationary-phase and exponentially growing bacteria and in mutY and mutM mutants, which accumulate mismatches between 8-oxoguanine (8-oxoG) and adenine residues in DNA. Conversely, GC --> TA transversion increased in mutL or mutS mutants in stationary phase. In contrast, overexpression of MutS did...

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Identifiers

PMID: 10940054
DOI: 10.1128/JB.182.17.5025-5028.2000
PMCID: PMC111390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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