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Article

DNA repair by Ogt alkyltransferase influences EMS mutational specificity.

Carcinogenesis - 1 Apr 1995

Vidal A, Abril N, Pueyo C

Abstract excerpt

Forward mutations induced by ethylmethane sulfonate (EMS) in the lacI gene of Escherichia coli were recovered from bacteria proficient or deficient in the alkyltransferase encoded by the constitutive ogt gene. EMS doses of 100 or 200 mM (Ogt+) and of 50 mM (Ogt-) were selected from the corresponding dose-response curves for DNA sequence analysis. A total of 239 induced mutations affecting the N-terminal region of...

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Identifiers

PMID: 7728961
DOI: 10.1093/carcin/16.4.817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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